<p>Liposomal doxorubicin at a loading dose of 6 mg/kg was introduced into Balb/c-nu mice via either spleen injection or i.v. injection. After drug administration, the blood, liver, heart and kidney were collected from treated mice. Doxorubicin concentrations versus time in plasma (A), liver (B), heart (C) and Kidney (D) were determined by HPLC.</p
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by sy...
Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the...
<P>The tissue concentration of doxorubicin (adriamycin; ADM) and its major metabolite (aglyc...
<p>The concentration of doxorubicin in tumor tissue at each time point was higher after injection of...
Pharmacokinetic analysis of the distribution and concentration of adriamycin (ADM) in mouse plasma a...
Marafino, Benedict J. Jr., Shri N. Gin and David M. Siegel: Pharmacokinetics, covalent binding and s...
We have previously reported on lipo-some formulations with reduced up-take by the reticuloendothelia...
<p>Individual and mean sum total doxorubicin concentration in plasma, brain tumor, contralateral non...
AbstractThe pharmacokinetics (PK), biodistribution (BD), and therapeutic activity of pegylated lipos...
<p>The analysis was performed 48 hours post injection of the 7mg/kg dose of targeted and non-targete...
<p>Note. MP5-2-LD = mutant SP5-2 conjugated liposomal doxorubicin; SP5-2-LD = SP5-2 conjugated l...
Effects of multiple injections of liposomal doxorubicin on phar-macokinetics, therapeutic outcome, a...
The usefulness of liposomes (in neutral, positively and negatively charged forms) as a carrier for a...
Aims were to observe pharmacokinetics, pharmacodynamics, and toxicity for constructing a Sino-pegyla...
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by sy...
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by sy...
Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the...
<P>The tissue concentration of doxorubicin (adriamycin; ADM) and its major metabolite (aglyc...
<p>The concentration of doxorubicin in tumor tissue at each time point was higher after injection of...
Pharmacokinetic analysis of the distribution and concentration of adriamycin (ADM) in mouse plasma a...
Marafino, Benedict J. Jr., Shri N. Gin and David M. Siegel: Pharmacokinetics, covalent binding and s...
We have previously reported on lipo-some formulations with reduced up-take by the reticuloendothelia...
<p>Individual and mean sum total doxorubicin concentration in plasma, brain tumor, contralateral non...
AbstractThe pharmacokinetics (PK), biodistribution (BD), and therapeutic activity of pegylated lipos...
<p>The analysis was performed 48 hours post injection of the 7mg/kg dose of targeted and non-targete...
<p>Note. MP5-2-LD = mutant SP5-2 conjugated liposomal doxorubicin; SP5-2-LD = SP5-2 conjugated l...
Effects of multiple injections of liposomal doxorubicin on phar-macokinetics, therapeutic outcome, a...
The usefulness of liposomes (in neutral, positively and negatively charged forms) as a carrier for a...
Aims were to observe pharmacokinetics, pharmacodynamics, and toxicity for constructing a Sino-pegyla...
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by sy...
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited by sy...
Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the...
<P>The tissue concentration of doxorubicin (adriamycin; ADM) and its major metabolite (aglyc...