<p>(A) Gels showing amplified cDNA bands for different primers. The cDNA was prepared from the mRNA isolated from the control and treated sides of the striatum of the embryonic stem cells, undifferentiated (ES) and 7 days differentiated (7 d) cell transplanted groups. Ratios of the band intensities for GFAP (B), GDNF (C), IBA-1 (D), CD11b-A (E) and CD11b-B (F) as normalised with hypoxanthine-guanine phosphoribosyl transferase (HGPRT) and fold change of band intensities of the treated side compared to the control side was calculated for each animal. Results are presented as Mean ± SEM. *<i>p</i>≤0.05 vs control side of the same group, <sup>#</sup><i>p</i>≤0.05 vs treated side of the ES transplanted group, n = 3.</p
Background Ex vivo gene therapy and cell replacement in the nervous system may provide therapeutic o...
<p>A) Representative pictures from the four groups of Protocol 2 are shown. A strong increase of Ki6...
<p>Fluorescence microscopic analysis of EGFP-labeled rMSCs striatal sections in Lv-null-MSCs group a...
<p>Undifferentiated and differentiated embryonic stem cells (ES), and 7 days and 10 days differentia...
<p>(<b>A</b>) Cell type composition (NeuN, neurons; GFAP, astrocytes) quantified by confocal IF anal...
<p>There were more eGFP<sup>+</sup>, Nestin<sup>+</sup>, eGFP<sup>+</sup>/Nestin<sup>+</sup>, TH<sup...
<p>Striata, ipsilateral to the side of rotenone infusion were grafted with vehicle without any cells...
A systematic characterization of the spatio-temporal gene expression during human neurodevelopment i...
A systematic characterization of the spatio-temporal gene expression during human neurodevelopment i...
<p>Panel 1. Light Microscopy images at 40X magnification of BM-MSC (1a-c), CB-MSC (3a-c), hE-MSC (5a...
To investigate the ability of human GFAP positive neural progenitor cell line from the subventricula...
<p><b>(A)</b><i>In situ</i> hybridization showing <i>Gdnf</i> mRNA expression in thalamic nuclei at ...
<p>Representative photomicrograph illustrating that many transplanted cells survived in the striatum...
Huntington's disease (HD) is a neurodegenerative condition in which the predominant loss of neurons ...
<p>Striatal sections of 20 µm thickness of embryonic stem cells, undifferentiated (ES; A–H) and 7 da...
Background Ex vivo gene therapy and cell replacement in the nervous system may provide therapeutic o...
<p>A) Representative pictures from the four groups of Protocol 2 are shown. A strong increase of Ki6...
<p>Fluorescence microscopic analysis of EGFP-labeled rMSCs striatal sections in Lv-null-MSCs group a...
<p>Undifferentiated and differentiated embryonic stem cells (ES), and 7 days and 10 days differentia...
<p>(<b>A</b>) Cell type composition (NeuN, neurons; GFAP, astrocytes) quantified by confocal IF anal...
<p>There were more eGFP<sup>+</sup>, Nestin<sup>+</sup>, eGFP<sup>+</sup>/Nestin<sup>+</sup>, TH<sup...
<p>Striata, ipsilateral to the side of rotenone infusion were grafted with vehicle without any cells...
A systematic characterization of the spatio-temporal gene expression during human neurodevelopment i...
A systematic characterization of the spatio-temporal gene expression during human neurodevelopment i...
<p>Panel 1. Light Microscopy images at 40X magnification of BM-MSC (1a-c), CB-MSC (3a-c), hE-MSC (5a...
To investigate the ability of human GFAP positive neural progenitor cell line from the subventricula...
<p><b>(A)</b><i>In situ</i> hybridization showing <i>Gdnf</i> mRNA expression in thalamic nuclei at ...
<p>Representative photomicrograph illustrating that many transplanted cells survived in the striatum...
Huntington's disease (HD) is a neurodegenerative condition in which the predominant loss of neurons ...
<p>Striatal sections of 20 µm thickness of embryonic stem cells, undifferentiated (ES; A–H) and 7 da...
Background Ex vivo gene therapy and cell replacement in the nervous system may provide therapeutic o...
<p>A) Representative pictures from the four groups of Protocol 2 are shown. A strong increase of Ki6...
<p>Fluorescence microscopic analysis of EGFP-labeled rMSCs striatal sections in Lv-null-MSCs group a...