<i>H. pylori</i>-stimulated BMDCs from TLR2KO mice produced lower levels of proinflammatory cytokines.

<p>BMDCs derived from C57BL/6 mice (wild type, WT) and TLR2KO mice were stimulated with a blank control, live <i>H</i>. <i>pylori</i> (HP-L), and <i>H</i>. <i>pylori</i> sonicate (HP-S). At 18 h post infection, the supernatants were collected from medium alone and HP-L- and HP-S–treated BMDCs. The concentrations of IL-12p70 (<b>a</b>), TNF-α (<b>b</b>), IL-6 (<b>c</b>), and IL-23p19 (<b>d</b>) in supernatant were determined by enzyme-linked immune absorbent assay (ELISA). Data are representative of the results of three independent experiments. Data are presented as means ± SEM of 3 mice in vitro. ^*<i>P</i> < 0.05, ^**<i>P</i> < 0.01, and ^***<i>P</i> < 0.01 compared with WT mice.