Time course of FADD expression in each group post-myocardial ischemia/reperfusion (I/R).

<p>(A) Top: Representative photomicrographs of FADD expression in cardiac tissue by western blot in WT C57/BL6 (lanes 1–2) and FADD^+/−-FADD∶GFP-MHC-Cre⁻ (lanes 3–4) control mice, FADD^−/−-FADD∶GFP-MHC-Cre⁻ (NLC, line 5–6) and FADD^−/−-FADD∶GFP-MHC-Cre⁺ (FADD^−/−, line 7–8) mice. Bottom: Ratio of FADD expression (FADD or FADD+FADD∶GFP to GAPDH). (B) Top: Representative photomicrographs of FADD∶GFP expression in cardiac tissue pre- and post-MI/R by western blot in FADD^−/−-FADD∶GFP-MHC-Cre⁻ (NLC) and FADD^−/−-FADD∶GFP-MHC-Cre⁺ (FADD^−/−) groups. Bottom: Ratio of FADD expression (FADD∶GFP to GAPDH). n = 4. **<i>P</i><0.01 vs. FADD^−/−-FADD∶GFP-MHC-Cre⁻ (NLC). ^#<i>P</i><0.05 vs pre-I/R condition in NLC and FADD^−/− groups respectively, n = 4.