<div><p>A) Genome-wide distribution of LOH events in each adrenocortical tumor according to the hidden markov model (Partek GS). ACA=adenoma (n=24, total number of LOH=23). ACC=carcinoma (n=22, total number of LOH=2439).</p> <p>B) Genome-wide distribution of copy neutral LOH identified by merged analysis between copy number alteration and LOH analysis.</p></div
The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We use...
<p>Monoclonal adrenocortical lesions show inverse correlation between proliferation and apoptosis, w...
Context: Adrenocortical adenomas (ACAs) are among the most frequent human neoplasias. Genetic altera...
<div><p>In the upper panel, the percentage of samples affected by different alterations is reported....
Genomic aberrations such as copy number alterations (CNA) and loss of heterozygosity (LOH) are hallm...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Identifying regions of loss-of-heterozygosity (LOH) in a tumor sample is a challenging problem. Stat...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Loss of heterozygosity (LOH) is a common genetic event in cancer development, and is known to be inv...
Pediatric adrenocortical carcinoma is a rare malignancy with poor prognosis. Here we analyze 37 adre...
Loss of heterozygosity (LOH) is a common genetic lesion found in many human neoplasms. Extending inv...
Pan-cancer studies sketched the genomic landscape of the tumor types spectrum. We delineated the pur...
The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We use...
Pathogenesis of autonomous steroid secretion and adrenocortical tumorigenesis remains partially obsc...
The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We use...
<p>Monoclonal adrenocortical lesions show inverse correlation between proliferation and apoptosis, w...
Context: Adrenocortical adenomas (ACAs) are among the most frequent human neoplasias. Genetic altera...
<div><p>In the upper panel, the percentage of samples affected by different alterations is reported....
Genomic aberrations such as copy number alterations (CNA) and loss of heterozygosity (LOH) are hallm...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Identifying regions of loss-of-heterozygosity (LOH) in a tumor sample is a challenging problem. Stat...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Adrenocortical tumors consist of benign adenomas and highly malignant carcinomas with a still incomp...
Loss of heterozygosity (LOH) is a common genetic event in cancer development, and is known to be inv...
Pediatric adrenocortical carcinoma is a rare malignancy with poor prognosis. Here we analyze 37 adre...
Loss of heterozygosity (LOH) is a common genetic lesion found in many human neoplasms. Extending inv...
Pan-cancer studies sketched the genomic landscape of the tumor types spectrum. We delineated the pur...
The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We use...
Pathogenesis of autonomous steroid secretion and adrenocortical tumorigenesis remains partially obsc...
The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We use...
<p>Monoclonal adrenocortical lesions show inverse correlation between proliferation and apoptosis, w...
Context: Adrenocortical adenomas (ACAs) are among the most frequent human neoplasias. Genetic altera...