<i>In vivo</i> ventricular structure, function and heart rate were similar in sham and OVX mice.

<p><b>A</b>. M-mode images of cardiac function from sham and OVX mice. The white lines in each image denote the lumen edges in systole and diastole. <b>B</b>,<b>C</b>,<b>D</b>. Left ventricular internal diameter in systole (LVIDs), left ventricular posterior wall thickness in systole (LVPWs) and interventricular septal thickness in systole (IVSs) were similar in sham and OVX hearts. <b>E</b>,<b>F</b>. Left ventricular internal diameter in diastole (LVIDd) and left ventricular posterior wall thickness in diastole (LVPWd) were unaffected by OVX. <b>G</b>. By contrast, interventricular septal thickness in diastole (IVSd) was reduced significantly by OVX. <b>H</b>,<b>I</b>,<b>J</b>. Mean values for ejection fraction, left ventricular fractional shortening and heart rate were identical in sham and OVX mice (n=6 sham and 6 OVX mice; *p<0.05; t-test).