Relative number of RNA transcripts of markers in the brains of mice infected with WNV-FIN, Ita09 and 578/10.

<p>Sick animals were euthanized within days 6-14 upon reaching humane endpoints or on day 20 post-infection in the absence of clinical signs. Transcripts were compared with animals that survived WNV infection (day 20 p.i) and that were either positive or negative for viral antigen in the brain. Mean is indicated by a cross and median by a line in the boxes. The box represents the interquartile range. * <i>P</i> <0.05, ** <i>P</i> <0.01, *** <i>P</i> <0.001. Abbreviations: TNF = tumour necrosis factor; MMP = matrix metalloproteinase; Nptx = neural pentraxin; Ptx = pentraxin.