A representative case of polypoidal choroidal vasculopathy with a single polypoidal lesion.

<p>(Top left) A fundus photograph shows a reddish-orange lesion (arrow) surrounded by subretinal hemorrhage and retinal pigment epithelium depigmentation in the macular area (Top middle). FFA shows saccular hyperfluorescence (arrow) and irregular transmitted fluorescence (arrowheads) in the macular area (Middle left). Early phase of ICGA shows a polypoidal lesion, saccular slight hyperfluorescence (arrow) and dilated choroidal blood vessels (arrowheads) in the macular area (Middle middle). The late phase of ICGA shows the “washout” of a polypoidal lesion (arrow) and hypofluorescence region (arrowheads) corresponding with transmitted fluorescence in the FFA (Bottom left). Both horizontal and vertical cross-sectional OCT scans show a localized, steep, protruded polypoidal lesion and the disruption of the outer photoreceptor layer (arrows) (Top right). FAF shows granular hypoautofluorescence (black arrowheads) and confluent hypoautofluorescence (white arrowhead), which correspond to the transmitted fluorescence in FFA and the hypofluorescence region in ICGA. Moreover, that FAF shows an oval-shaped hyperautofluorescence (black arrow) at the site of the polypoidal lesion and a hyperautofluorescent ring (white arrow) surrounding the confluent hypoautofluorescence (white arrowhead) (Bottom right). Retro-mode imaging shows a well-defined polypoidal lesion (arrow) and an irregular, well-defined, ragged surface area (arrowheads), which correspond well with the ICGA.