Sweat gland LRCs are localized in the acinar gland region of SGs.

<p>(A,B) H2BGFP is expressed in the epidermis and sweat glands before doxycycline treatment. (C,D) Sweat gland LRCs are found in the acinar gland region after 4 weeks of chase with doxycycline. (E,F) Tissue histology on sections with H&E staining. Abbreviations: LRCs, label-retaining cells; H2BGFP, histone 2B conjugated with green fluorescent protein; H&E, hematoxylin and eosin staining.