<p>(A) IL-33 mRNA found in cell populations FACS sorted from the lung at 12 d.p.i.. (B) IL-33 protein in NKT as detected by intracellular staining (filled) compared to FMO control (shaded gray) at 12 d.p.i. (C) Total NKT cells identified in the influenza-infected lung as defined by CD3 and CD1d tetramer staining. (D) BAL IL-5 levels at 7 d.p.i. in indicated mouse strains. Data is representative of at least 2 independent experiments with 2–3 mice each. mRNA was collected from pooled, sorted cell populations from >5 mice. Bars = +/− SEM. *p<.05.</p
<p>Mouse inflammatory cytokines (MCP-1, TNΦα, IFNγ and IL-12p70) were evaluated in lung homogenates ...
<p>(<b>A</b>) IL-33 by ELISA in lung homogenates of WT mice at day 8. BALB/c WT and IL-33 KO mice we...
<p>Mice were intranasally infected with a sub-lethal dose of influenza A/PR8/34 and bronchoalveolar ...
<p>(A) Alveolar macrophages (AM) and NKT were FACS sorted from the lungs at the indicated days and a...
<p>Lungs from infected CD1d<sup>−/−</sup> or C57BL/6 (WT C57) were harvested at 7 (A–C) and 12 d.p.i...
International audienceIL-33, a novel IL-1 family member, is crucially expressed and involved in pulm...
<p>Beginning on the day of infection, mice received i.v. injections of either PBS vehicle control or...
(A) The amounts of IL-33 in naïve mouse whole lung homogenates were measured using ELISA at differen...
International audienceIL-33 has recently been identified as a cytokine endowed with pro-Th2 function...
<p>IFNγ-YFP reporter mice (GREAT mice, A-F), IFNγ-YFP.IL12p35<sup>-/-</sup> (A,D,E) or C57BL/6 mice ...
<p>WT and β6 KO mice were infected with influenza as described in <a href="http://www.plospathogens....
On day 11, the mice received 3.1 million purified NK/NKT cells containing 1 million WT NKT cells or ...
<p>WT and NKC<sup>KD</sup> mice were infected intranasally with 600 PFU of FM-MA virus. Single-cell ...
<p>Mice were intranasally infected with a 0.5LD<sub>50</sub> Influenza A/PR8/34 virus and sacrificed...
<div><p>Respiratory virus infections, such as influenza, typically induce a robust type I (pro-infla...
<p>Mouse inflammatory cytokines (MCP-1, TNΦα, IFNγ and IL-12p70) were evaluated in lung homogenates ...
<p>(<b>A</b>) IL-33 by ELISA in lung homogenates of WT mice at day 8. BALB/c WT and IL-33 KO mice we...
<p>Mice were intranasally infected with a sub-lethal dose of influenza A/PR8/34 and bronchoalveolar ...
<p>(A) Alveolar macrophages (AM) and NKT were FACS sorted from the lungs at the indicated days and a...
<p>Lungs from infected CD1d<sup>−/−</sup> or C57BL/6 (WT C57) were harvested at 7 (A–C) and 12 d.p.i...
International audienceIL-33, a novel IL-1 family member, is crucially expressed and involved in pulm...
<p>Beginning on the day of infection, mice received i.v. injections of either PBS vehicle control or...
(A) The amounts of IL-33 in naïve mouse whole lung homogenates were measured using ELISA at differen...
International audienceIL-33 has recently been identified as a cytokine endowed with pro-Th2 function...
<p>IFNγ-YFP reporter mice (GREAT mice, A-F), IFNγ-YFP.IL12p35<sup>-/-</sup> (A,D,E) or C57BL/6 mice ...
<p>WT and β6 KO mice were infected with influenza as described in <a href="http://www.plospathogens....
On day 11, the mice received 3.1 million purified NK/NKT cells containing 1 million WT NKT cells or ...
<p>WT and NKC<sup>KD</sup> mice were infected intranasally with 600 PFU of FM-MA virus. Single-cell ...
<p>Mice were intranasally infected with a 0.5LD<sub>50</sub> Influenza A/PR8/34 virus and sacrificed...
<div><p>Respiratory virus infections, such as influenza, typically induce a robust type I (pro-infla...
<p>Mouse inflammatory cytokines (MCP-1, TNΦα, IFNγ and IL-12p70) were evaluated in lung homogenates ...
<p>(<b>A</b>) IL-33 by ELISA in lung homogenates of WT mice at day 8. BALB/c WT and IL-33 KO mice we...
<p>Mice were intranasally infected with a sub-lethal dose of influenza A/PR8/34 and bronchoalveolar ...