Resveratrol inhibited T cell activation and antigen-specific antibody production in vivo.

<p>(<b>a</b>) Collagen-specific IgM in the serum from immunized mice was detected by ELISA. (<b>b</b>) The proliferation of collagen-specific T cell prepared from collagen-immunized mice spleen were measured through BrdU proliferation assay. (<b>c</b>–<b>f</b>) The cytokines in the serum from mice immunized with collagen were detected by ELISA (*<i>P</i> < 0.05, ** <i>P</i> < 0.01, ***<i>P</i> < 0.001). The data shown are representative of three independent experiments.