<p>(<b>A</b>) RT-PCR of lymphoid-specific gene expression in <i>ex </i><i>vivo</i> differentiated B220<sup>+</sup> CD11c<sup>+</sup> pDCs from <i>Gfi1</i><sup><i>f/f</i></sup><i>; Gfi1b</i><sup><i>f/f</i></sup><i>; ERCre</i> mice untreated (WT) and treated (KO) with tamoxifen. RNA isolated from primary B (B) or T (T) cells were used as controls. (<b>B</b>) Quantitative RT-PCR of pDC-specific genes in <i>ex </i><i>vivo</i> differentiated B220<sup>+</sup> CD11c<sup>+</sup> pDCs from <i>Gfi1</i><sup><i>f/f</i></sup><i>; Gfi1b</i><sup><i>f/f</i></sup><i>; ERCre</i> mice untreated (WT) and treated (KO) with tamoxifen. Expression values in arbitrary units are normalized to <i>Hprt</i> transcript abundance.</p
Mouse models (that develop or can be stimulated to develop lymphomas) are used to examine cancer-rel...
<p>(<b>A</b>) A diagram depicting the floxed <i>Meis1</i> allele. <i>LoxP</i> sites (arrowheads) wer...
<p>(A) Flow cytometry analysis was performed on bone marrow cells to subfractionate B220<sup>+</sup>...
<p>(<b>A</b>) Quantitative RT-PCR analysis of <i>Rag1</i> transcript levels in sorted B220<sup>+</su...
<p>(<b>A</b>) Flow cytometric analysis of VEX expression in B cells derived from the bone marrow of ...
<p>(A) LMPPs from WT, KI, KD and KO were sorted and cultured on stromal OP9 cells in the presence of...
<p>(A) FACS analysis of LSK cells. BM cells from WT, KI, Het, KD and KO mice were analyzed for Lin<s...
<p>A: Protocol used to efficiently generate adult <i>Gfi1b</i>-KO mice using tamoxifen. Eight week o...
<p>(A). Q-RT-PCR quantification of <i>Gcsf</i> expression in spleen normalized to <i>Hprt</i> expres...
<p>(A) Diagram illustrating that CKO in OL cell lineage results in the loss of Prox1 and the express...
<p><b>(A)</b> The results of the quantitative RT-PCR analysis of the <i>Gfi1</i> mRNA expression in ...
<p>(<b>A</b>) <i>Pdk1-4</i> expression in LSK cells transduced with <i>caHif-1α</i> or with empty ve...
<p><b>(A)</b><i>Hes1</i> and <i>Ptcra</i> mRNA expression in BM pDCs from 4 WT and 5 (Ik<sup>L/L</su...
<p>CD45<sup>+</sup>B220<sup>+</sup>440c<sup>+</sup> pDCs were sorted from bone marrow of <i>Apoe</i>...
<p>(A) Schematic for ICN colony forming unit (CFU) assay +/− Gfi1. CFU from FACS sorted ICN<sup>+</s...
Mouse models (that develop or can be stimulated to develop lymphomas) are used to examine cancer-rel...
<p>(<b>A</b>) A diagram depicting the floxed <i>Meis1</i> allele. <i>LoxP</i> sites (arrowheads) wer...
<p>(A) Flow cytometry analysis was performed on bone marrow cells to subfractionate B220<sup>+</sup>...
<p>(<b>A</b>) Quantitative RT-PCR analysis of <i>Rag1</i> transcript levels in sorted B220<sup>+</su...
<p>(<b>A</b>) Flow cytometric analysis of VEX expression in B cells derived from the bone marrow of ...
<p>(A) LMPPs from WT, KI, KD and KO were sorted and cultured on stromal OP9 cells in the presence of...
<p>(A) FACS analysis of LSK cells. BM cells from WT, KI, Het, KD and KO mice were analyzed for Lin<s...
<p>A: Protocol used to efficiently generate adult <i>Gfi1b</i>-KO mice using tamoxifen. Eight week o...
<p>(A). Q-RT-PCR quantification of <i>Gcsf</i> expression in spleen normalized to <i>Hprt</i> expres...
<p>(A) Diagram illustrating that CKO in OL cell lineage results in the loss of Prox1 and the express...
<p><b>(A)</b> The results of the quantitative RT-PCR analysis of the <i>Gfi1</i> mRNA expression in ...
<p>(<b>A</b>) <i>Pdk1-4</i> expression in LSK cells transduced with <i>caHif-1α</i> or with empty ve...
<p><b>(A)</b><i>Hes1</i> and <i>Ptcra</i> mRNA expression in BM pDCs from 4 WT and 5 (Ik<sup>L/L</su...
<p>CD45<sup>+</sup>B220<sup>+</sup>440c<sup>+</sup> pDCs were sorted from bone marrow of <i>Apoe</i>...
<p>(A) Schematic for ICN colony forming unit (CFU) assay +/− Gfi1. CFU from FACS sorted ICN<sup>+</s...
Mouse models (that develop or can be stimulated to develop lymphomas) are used to examine cancer-rel...
<p>(<b>A</b>) A diagram depicting the floxed <i>Meis1</i> allele. <i>LoxP</i> sites (arrowheads) wer...
<p>(A) Flow cytometry analysis was performed on bone marrow cells to subfractionate B220<sup>+</sup>...