Relationships between basal mEPSC amplitude, peak change and duration of response to HFS.

<div><p>In all graphs in this figure and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077402#pone-0077402-g003" target="_blank">Figure 3</a>, each circle denotes a single neuron. p values are indicated within graphs if they reached a significance.</p><p>A-C) Linear regression analysis showing that the basal mEPSC amplitude is not related to the absolute amplitude change during the 1^st min post-HFS (A) or duration of the change (B). In contrast, a negative correlation exists between the amplitude in baseline control and 1^st min post-HFS conditions upon normalizing the amplitude response to control values (C).</p><p>D and E) Linear regression analysis showing that both absolute (D) and normalized (relative; E) responses during the 1^st min post-HFS are positively related to how long the response persists.</p>