Data obtained using BEAST analysis, the Poisson Fitter tool, and serological analysis are expressed as the number of days between the estimated date of HIV-1 transmission and HIV-1 diagnosis in the newly-infected partner. These data are also shown in Figure 1B, expressed as days before or after ART initiation in the index.

a<p>HIV-1 diagnosis indicates the number of days between ART initiation in the index and HIV-1 diagnosis in the partner (first HIV-positive sample).</p>b<p>Estimate of the time between HIV-1 transmission and HIV-1 diagnosis in the newly-infected partner based on BEAST analysis.</p>c<p>Estimate of the time between HIV-1 transmission and HIV-1 diagnosis in the newly-infected partner based on use of the Poisson Fitter (Case A only).</p>d<p>The table shows the earliest and average number of days between HIV-1 transmission and the Fiebig stage of each of the newly-infected partners, based on Western blot analysis. The partner in Case A was Fiebig stage V; the partner in Case B was Fiebig Stage VI <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071557#pone.0071557-Fiebig1" target="_blank">[12]</a>; a 7-day eclipse period was included in the calculations.