Comparison of mean regional nT1 values from the upper and lower lung regions for the CF patients and healthy volunteers.

<p>A significant reduction in mean (SD) nT1 (**p = 0.001) was observed in the upper right (UR) [.914 (.037)] and upper left (UL) [0.906 (.040)] lung regions (black bars) for the CF patients (n = 10) in comparison to the healthy control subjects (n = 5) UR [.983 (.003)] and UL [0.984 (.011)] lung regions (open bars). The mean nT1 in the lower right (LR) and lower left (LL) lung regions was also significantly reduced for the CF patients in comparison to healthy volunteers (*p<0.05). Importantly, these differences were observed despite normal spirometry in both groups.