Genotype distribution of <i>Lrig</i> mutant animals.

<p>Mice were generated from intercrosses between animals carrying <i>Lrig1</i> and <i>Lrig2</i> (top) or <i>Lrig1</i> and <i>Lrig3</i> mutant alleles (top). The number of mice carrying each genotype at postnatal day 7 (P7) and at 6 weeks is indicated, out of a total of 253 offspring from <i>Lrig1</i>;<i>Lrig2</i> intercrosses and 181 offspring from <i>Lrig1</i>;<i>Lrig3</i> intercrosses. For each genotype, the number of mice that is expected from this kind of intercross in indicated in parentheses. χ-squared tests confirmed that the observed distribution of genotypes is significantly different from the expected distribution.