Effects of MLPL gene transfer on energy metabolism of <i>extensor digitorum longus</i>.

<p>Variations in expression of key functional genes related to energy metabolism (A) and transcription factors (B), AMPK, phospho-AMPK, and PGC-1α protein levels in <i>extensor </i><i>digitorum </i><i>longus</i> (C and D) muscle after MLPL gene transfer <i>in </i><i>vivo</i> by HD at a dose of 15µg per animal. Each value represents mean <u>+</u> SEM of five or three mice. * and ** indicate significant difference relative to the control at the same time point at p<0.05 and p<0.01, respectively.