Cyto-architectural properties of Cdk5, activated Cdk5 (pCdk5) and p35.
- Alessandra Bosutti (464771)
- Jie Qi (53195)
- Roberta Pennucci (83950)
- David Bolton (464376)
- Sabine Matou (41463)
- Kamela Ali (464772)
- Li-Huei Tsai (203109)
- Jerzy Krupinski (83949)
- Eugene B. Petcu (464773)
- Joan Montaner (134700)
- Raid Al Baradie (464774)
- Francesca Caccuri (354808)
- Arnaldo Caruso (354812)
- Giulio Alessandri (191605)
- Shant Kumar (83955)
- Cristina Rodriguez (464775)
- Jose Martinez-Gonzalez (464776)
- Mark Slevin (41459)
Publication date
September 2013
DOIAbstract
<p>(A) Representative image showing Cdk5 localization at the tip of actin fibre (arrow) in early spreading (Ai). (B) Panel showing pCdk5 (pTyr<sub>(Ser15)</sub>) localization with actin tips (arrows) and fibre in early (Bi) and late (Bii) spreading and in moving (Biii) cells. (c) p35 co-localized with actin stress fibres and was distributed from the nucleus (Ci) as the cell spreads culminating in filament tips (arrows in merge) in moving (Ciii) and late (Cii) spreading cells. Immunofluorescence confocal microscope analysis. Objective 65x. Original magnification in merge, x 240. Bars, 25 µm. Original magnification in Ai merge, x 290. Original magnification in merge in panel A, x300. Each experiment was performed in triplicate.</p
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