<p>BALB/c mice (n = 10) were infected intradermally (ID) with 5×10<sup>7</sup> cfu WT (□) or Δ<i>hla</i> (▪). Lesion sizes were measured up to 21 days post infection, and graphed as mean values ± standard deviation. Lesion sizes were significantly smaller for Δ<i>hla</i> up to day 10 (p≤ 0.007). Representative skin lesion pictures were taken on day 7.</p
<p>(<b>A</b>) Western blot of IL-33 in skin extracts from <i>S.aureus</i>-infected patients. Samples...
<p>Mice were vaccinated with 10 µg of a 1∶1 suspension of peptide 2 and peptide 4 and inoculated wit...
B6HLA mice were administered ~5 × 107 CFUs of wildtype S. pyogenes MGAS8232, or the hasA mutant, or ...
<p>BABL/c mice (n = 10) were passively immunized intraperitoneally (IP) anti-AT mAb 2A3 (10 mg/kg) (...
(Ai) Representative images of dermonecrotic lesion size in mice (BALB/cJ) after 6 days postinfection...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
<p>(A) Fluorescence confocal imaging of humanized mouse spleen showing separate mouse CD45 and human...
<p>(A) Athymic nude mice from the Balb/c background had smaller lesions, compared wild type Balb/c m...
<p>Mice (n = 4) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Median fluorescence intensity (MFI) values reflect levels of IgG against 25 <i>S</i>. <i>aureus</...
<p>Wild type and athymic nude mice from the Balb/c background (n=10 mice/group) were sacrificed 3 da...
<p>(A) There was no difference in lesion size between C57Bl/6j (wild type) and TCR βδ (-/-) mice aft...
<p>BALB/c mice (n = 10) were immunized IP with anti-AT mAb 2A3 (▪) or isotype control R347 (□) at 10...
<p>(A) Data are presented as mean total lesion size (mm<sup>2</sup>) ± SEM and are representative of...
<p>(<b>A</b>) Western blot of IL-33 in skin extracts from <i>S.aureus</i>-infected patients. Samples...
<p>Mice were vaccinated with 10 µg of a 1∶1 suspension of peptide 2 and peptide 4 and inoculated wit...
B6HLA mice were administered ~5 × 107 CFUs of wildtype S. pyogenes MGAS8232, or the hasA mutant, or ...
<p>BABL/c mice (n = 10) were passively immunized intraperitoneally (IP) anti-AT mAb 2A3 (10 mg/kg) (...
(Ai) Representative images of dermonecrotic lesion size in mice (BALB/cJ) after 6 days postinfection...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
<p>(A) Fluorescence confocal imaging of humanized mouse spleen showing separate mouse CD45 and human...
<p>(A) Athymic nude mice from the Balb/c background had smaller lesions, compared wild type Balb/c m...
<p>Mice (n = 4) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Median fluorescence intensity (MFI) values reflect levels of IgG against 25 <i>S</i>. <i>aureus</...
<p>Wild type and athymic nude mice from the Balb/c background (n=10 mice/group) were sacrificed 3 da...
<p>(A) There was no difference in lesion size between C57Bl/6j (wild type) and TCR βδ (-/-) mice aft...
<p>BALB/c mice (n = 10) were immunized IP with anti-AT mAb 2A3 (▪) or isotype control R347 (□) at 10...
<p>(A) Data are presented as mean total lesion size (mm<sup>2</sup>) ± SEM and are representative of...
<p>(<b>A</b>) Western blot of IL-33 in skin extracts from <i>S.aureus</i>-infected patients. Samples...
<p>Mice were vaccinated with 10 µg of a 1∶1 suspension of peptide 2 and peptide 4 and inoculated wit...
B6HLA mice were administered ~5 × 107 CFUs of wildtype S. pyogenes MGAS8232, or the hasA mutant, or ...