TQ induces apoptosis in breast tumor xenograft with down-regulation of anti-apoptotic proteins.

<p>(A) H&E staining of the tumor tissues. (B) TUNEL staining of the tumor tissues. The graph showed the average number of fluorescence dots of images from each treatment group. Values are means ± S.D. of three photographs. * p<0.05, ** p<0.01 compared to the vehicle group. (C) Ki67 immunohistochemical staining of the tumor tissues. The graph showed the average number of fluorescence dots of images from each treatment group. Values are means ± S.D. of three photographs. * p<0.05, ** p<0.01 compared to the vehicle group. (D) Western blot analysis showed the effect of drug treatments on the protein expression of various anti-apoptotic genes. Data are representative of at least three independent experiments.