Unexpectedly severe acute radiotherapy side effects are associated with single nucleotide polymorphisms of the melanocortin-1 receptor
- Fogarty, Gerald B.
- Muddle, Rory
- Sprung, Carl N.
- Chen, Wei
- Duffy, David
- Sturm, Richard A.
- McKay, Michael J.
Publication date
July 2010
DOI Publisher
Elsevier BV ISSN
0360-3016 Citation count (estimate)
15Abstract
Purpose: The melanocortin-1 receptor (MC1R) regulates melanin biogenesis. Deoxyribonucleic acid sequence variants in the form of single nucleotide polymorphisms (SNPs) of MC1R affect melanin expression and are linked to skin phenotype. We aimed to determine whether SNPs of MC1R were associated with unexpectedly severe ionizing radiation reactions
Add to ORKG