Ablation of enhanced IL-13 production by CD4+ T-cells in <i>Itgb8 (CD11c-Cre)</i> mice restores susceptibility to infection with <i>T. muris</i>.

<p>(<i>A</i>) IL-13 production by LILP CD4+ T-cells isolated day 3 post-infection (p.i.) with a chronic dose of <i>T. muris</i> eggs in IL-4−/− control and <i>Itgb8 (CD11c-Cre)</i> IL-4−/− mice. Representative flow cytometry plots and mean data are displayed. Data (n = 5–6 mice per group) are from two independent experiments. Data (n = 5–6) are from two independent experiments performed. (<i>B</i>) Worm burdens from IL-4−/− and <i>Itgb8 (CD11c-Cre)</i> IL-4−/− mice at day 14 p.i. with a chronic dose of <i>T. muris</i> eggs. Data (n = 5–6 mice per group) are from two independent experiments. **, P<0.01; N.S., not significant via Student's <i>t</i> –test for the indicated comparisons between groups, error bars represent SE of means.