Pd-Catalyzed Cyclization and Carbene Migratory Insertion: New Approach to 3‑Vinylindoles and 3‑Vinylbenzofurans

A Pd-catalyzed stereoselective synthesis of 3-vinylindoles and 3-vinylbenzofurans has been developed. The reaction merges the alkyne-based Pd-catalyzed cyclization and Pd carbene migratory insertion in a single catalytic cycle, generating a C–C single bond and a CC double bond in one operation