<p>MCF-7 cells were incubated in the absence or presence of different concentrations of ansamitocin P3 for 24 h. Interphase (A) and mitotic (B) microtubules are shown. Scale bar is 10 µm.</p
<p>(<b>A</b>) MDCK.Kif3a-i cells were grown to confluency (48 hours), fixed 6 hours after wounding a...
<p>HUVECs were treated with KML001, or no drug as the control, for 24 h at the indicated concentrati...
SummaryFor mammalian somatic cells, the importance of microtubule cytoskeleton integrity during inte...
<p>Ansamitocin P3 caused the accumulation of Mad 2 (A) and BubR1 (B). MCF-7 cells were incubated in ...
<p>(A) Inhibition of MCF-7 (▪), HeLa (▴), EMT-6/AR1 (•) and MDA-MB-231(▾) cell proliferation by ansa...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
<p>(A) Cells were treated without and with 40 µM BCFMT for 3 h and microtubules were stained using a...
<p>(A) Ansamitocin P3 treatment caused an increase in the expression level of p53 in MCF-7 cells. La...
<p>Double immunoflourecence was done to determine the compounds' effect after 24 h on microtubule dy...
Shown are exemplary micrographs of cells treated with 10 μM nocodazole (A, B) and control cells trea...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Human monocytes, which contain few interphase microtubules (35.+/- 7.7), were used to study the dyna...
Microtubules are dynamic polymers which play important roles in mitosis, cell locomotion, and the de...
<p>(<b>A</b>) MDCK.Kif3a-i cells were grown to confluency (48 hours), fixed 6 hours after wounding a...
<p>HUVECs were treated with KML001, or no drug as the control, for 24 h at the indicated concentrati...
SummaryFor mammalian somatic cells, the importance of microtubule cytoskeleton integrity during inte...
<p>Ansamitocin P3 caused the accumulation of Mad 2 (A) and BubR1 (B). MCF-7 cells were incubated in ...
<p>(A) Inhibition of MCF-7 (▪), HeLa (▴), EMT-6/AR1 (•) and MDA-MB-231(▾) cell proliferation by ansa...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
<p>(A) Cells were treated without and with 40 µM BCFMT for 3 h and microtubules were stained using a...
<p>(A) Ansamitocin P3 treatment caused an increase in the expression level of p53 in MCF-7 cells. La...
<p>Double immunoflourecence was done to determine the compounds' effect after 24 h on microtubule dy...
Shown are exemplary micrographs of cells treated with 10 μM nocodazole (A, B) and control cells trea...
Maytansinoid conjugates are currently under different phases of clinical trials and have been showin...
Human monocytes, which contain few interphase microtubules (35.+/- 7.7), were used to study the dyna...
Microtubules are dynamic polymers which play important roles in mitosis, cell locomotion, and the de...
<p>(<b>A</b>) MDCK.Kif3a-i cells were grown to confluency (48 hours), fixed 6 hours after wounding a...
<p>HUVECs were treated with KML001, or no drug as the control, for 24 h at the indicated concentrati...
SummaryFor mammalian somatic cells, the importance of microtubule cytoskeleton integrity during inte...