NF-κB staining in perivascular macrophages in lung parenchyma a patient with idiopathic pulmonary arterial hypertension.

<p>Macrophages (CD68+ cells, brown) are seen surrounding a diseased pulmonary artery in a post-transplantation lung specimen from a patient with idiopathic pulmonary arterial hypertension (PAH). Some of these cells exhibit nuclear p65-positive staining (pink staining, black arrow) i.e. show evidence of NF-κB activation; others demonstrate p65-negative staining (CD-68 brown only with no pink counter-staining, white arrow). In addition, small mononuclear cells (lymphocytes) stain avidly for p65. Magnification x200.