<p>Numbers of macrophages per 100<sup>2</sup> of lung parenchyma were increased in pulmonary arterial hypertension (PAH) vs. controls (49.0±4.5 vs. 7.95±1.9/100 mm<sup>2</sup>, ***p<0.001). Additionally, p65+ macrophages were increased in PAH compared with controls (52.4±2.15% vs. 71.6±2.98%, ***p<0.001) and in the nucleus in PAH compared to controls (3.5±1.3% vs. 16.9±2.5%, ***p<0.001). Results are expressed as mean ± SEM for 12 PAH and 14 control subjects.</p
Pulmonary hypertension (PH) is a complex, multifactorial disorder divided into five major subtypes a...
Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current...
International audiencePulmonary hypertension (PH) is a life-threatening condition arising from the l...
Background: Inflammation is known to be a feature of pulmonary arterial hypertension (PAH) and incre...
Background-Inflammation is a feature of pulmonary arterial hypertension (PAH), and increased circula...
Perivascular inflammation is a prominent pathologic feature in most animal models of pulmonary hyper...
AbstractInflammation underlies a wide variety of physiological and pathological processes. Acute inf...
Independent of the underlying cause, pulmonary hypertension (PH) remains adevastating condition that...
Objective: To determine whether global reduction of CD68 (cluster of differentiation) macrophages im...
To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic...
SummaryRationaleMounting data suggest that immune cell abnormalities participate in the pathogenesis...
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by remodeling of the pu...
Objective: To determine whether global reduction of CD68 (cluster of differentiation) macrophages i...
Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current...
Macrophages are proposed to play an important regulatory role in the pathogenesis of pulmonary arter...
Pulmonary hypertension (PH) is a complex, multifactorial disorder divided into five major subtypes a...
Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current...
International audiencePulmonary hypertension (PH) is a life-threatening condition arising from the l...
Background: Inflammation is known to be a feature of pulmonary arterial hypertension (PAH) and incre...
Background-Inflammation is a feature of pulmonary arterial hypertension (PAH), and increased circula...
Perivascular inflammation is a prominent pathologic feature in most animal models of pulmonary hyper...
AbstractInflammation underlies a wide variety of physiological and pathological processes. Acute inf...
Independent of the underlying cause, pulmonary hypertension (PH) remains adevastating condition that...
Objective: To determine whether global reduction of CD68 (cluster of differentiation) macrophages im...
To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic...
SummaryRationaleMounting data suggest that immune cell abnormalities participate in the pathogenesis...
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by remodeling of the pu...
Objective: To determine whether global reduction of CD68 (cluster of differentiation) macrophages i...
Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current...
Macrophages are proposed to play an important regulatory role in the pathogenesis of pulmonary arter...
Pulmonary hypertension (PH) is a complex, multifactorial disorder divided into five major subtypes a...
Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current...
International audiencePulmonary hypertension (PH) is a life-threatening condition arising from the l...