Effect of urantide on blood glucose levels and area under the curve (AUC) in the glucose tolerance test.

<p>KK mice were administrated urantide (30 µg/kg/day) for 14 days prior to calculation of glucose loading (A) and area under the curve (AUC) of changes in blood glucose levels (B). Control: C57BL/6J mice were treated with saline for 14 days; Urantide: C57BL/6J mice were treated with urantide for 14 days; KK:KK mice were treated with saline for 14 days; KK+Urantide: KK mice were treated with urantide for 14 days. Each value is mean±SD (n=6-8 for each group, *<i>P</i><0.05 vs control; ^#<i>P</i><0.05 vs KK group).