PPADS Inhibits Complement Mediated Cell Lysis.

<p><b>A</b>) Representative flow cytometry plots indicating number of Hepa1c1c7 cells taking up propidium iodide (PI) when incubated in 1% normal human serum (NHS) and various concentrations of PPADS (blue lines) or 0.9% NaCl (red lines). <b>B</b>) Mean values ± SEM of PPADS mediated reduction of NHS mediated cell lysis from 5 independent studies. Significant differences are shown as capped lines between vehicle control (0.9% NaCl, 0 µM PPADS) and the various concentrations of PPADS (*** p<0.0005, ** p<0.005, * p<0.05).