<p>IC, isocitrate; α-KG, α-ketoglutarate; NNT, nicotinamide nucleotide transhydrogenase; Pyr, pyruvate.</p
Objective: The glucose stimulation of insulin secretion (GSIS) by pancreatic β-cells critically depe...
In this thesis, three mouse models and cell culture techniques were used to investigate genetic fact...
Background and aim: Using GRX1‐roGFP2 as a reporter for changes in glutathione redox state, we recen...
Cytosolic NADPH may act as one of the signals that couple glucose metabolism to insulin secretion in...
A model for glucose sensing by pancreatic β-cells is developed and compared to the available experim...
<p>HP MIN6 cells increased glucose uptake at 1 mM glucose and decreased expression of some glycolyti...
Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-sec...
We integrated biological experimental data with mathematical modelling to gain insights into the rol...
Pancreatic β-cells secrete insulin in response to glucose. Intracellular glucose metabolism drives ...
<p>Insulin secretion is a fundamental process of pancreatic beta-cells required for the maintenance ...
The pancreatic β-cell secretes insulin in response to a raised blood glucose level. Deficiencies in ...
We integrated biological experimental data with mathematical modelling to gain insights into the rol...
Nicotinamide nucleotide transhydrogenase (NNT) couples proton influx to NADPH production in the mito...
<p>INS 832/13 cells were transfected with ScrAB, siIDHc#1 or siIDHc#2. A, IDHc mRNA expression level...
Iodoacetate inhibits glyceraldehyde-3-phosphate dehydrogenase activity in pancreatic islets and caus...
Objective: The glucose stimulation of insulin secretion (GSIS) by pancreatic β-cells critically depe...
In this thesis, three mouse models and cell culture techniques were used to investigate genetic fact...
Background and aim: Using GRX1‐roGFP2 as a reporter for changes in glutathione redox state, we recen...
Cytosolic NADPH may act as one of the signals that couple glucose metabolism to insulin secretion in...
A model for glucose sensing by pancreatic β-cells is developed and compared to the available experim...
<p>HP MIN6 cells increased glucose uptake at 1 mM glucose and decreased expression of some glycolyti...
Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-sec...
We integrated biological experimental data with mathematical modelling to gain insights into the rol...
Pancreatic β-cells secrete insulin in response to glucose. Intracellular glucose metabolism drives ...
<p>Insulin secretion is a fundamental process of pancreatic beta-cells required for the maintenance ...
The pancreatic β-cell secretes insulin in response to a raised blood glucose level. Deficiencies in ...
We integrated biological experimental data with mathematical modelling to gain insights into the rol...
Nicotinamide nucleotide transhydrogenase (NNT) couples proton influx to NADPH production in the mito...
<p>INS 832/13 cells were transfected with ScrAB, siIDHc#1 or siIDHc#2. A, IDHc mRNA expression level...
Iodoacetate inhibits glyceraldehyde-3-phosphate dehydrogenase activity in pancreatic islets and caus...
Objective: The glucose stimulation of insulin secretion (GSIS) by pancreatic β-cells critically depe...
In this thesis, three mouse models and cell culture techniques were used to investigate genetic fact...
Background and aim: Using GRX1‐roGFP2 as a reporter for changes in glutathione redox state, we recen...