Histological analyses of (A–C) MMP-2, (D-F) MMP-9, (G–I) COX-2, (J–L) RANK, (M–O) RANK-L, and (P–R) OPG in periodontal tissue of rats with periodontal disease.

<p>Rats subjected to saline are pictured in A, D, G, J, M, P; rats with periodontal disease are pictured in B, E, H, K, N, Q; rats with periodontal disease and treated with Atorvastatin (10 mg/kg) are pictured in C, F, I, L, O, R. 100× magnification, bar scale = 100 µm.