CCR2 deficiency reduces fibronectin expression in the kidney.

<p><b>A</b>. Representative photomicrographs of fibronectin immunostaining in the kidneys of WT and CCR2-KO mice at day 14 after UUO (original magnification X400). <b>B</b>. Quantitative analysis of interstitial fibronectin protein expression in the kidney sections of WT and CCR2-KO mice. ** <i>P</i> < 0.01 vs WT controls, ^#<i>P</i> < 0.05 vs WT UUO, and ⁺<i>P</i> < 0.05 vs KO UUO. n=6 per group. <b>C</b>. Representative Western blots show the protein levels of fibronectin in the kidneys of WT and CCR2-KO mice. <b>D</b>. Quantitative analysis of fibronectin protein expression in the kidneys of WT and CCR2-KO mice. ** <i>P</i> < 0.01 vs WT controls, ^#<i>P</i> < 0.05 vs WT UUO, and ⁺<i>P</i> < 0.05 vs KO UUO. n=5 per group.