Inhibition of PKC activity increases midgut epithelial barrier integrity in <i>Anopheles stephensi.</i>

<p>Mosquitoes were fed fluorescent beads (3–3.5 µM) in a blood meal in the presence or absence of PKC inhibitors and, at 72 h post-blood feeding bead numbers were quantified using flow cytometry. Dots represent bead numbers per three whole mosquitoes, means are indicated as bars. Midgut beads averaged 932±267 (mean ± SEM) for blood-fed controls and 377±66 and 305±127 for chelerythrine and Go6983 treated mosquitoes. Pairwise comparisons of treatments and matched controls were analyzed by Student’s t-test, p-values are shown.