UPEC-induced soluble-dependent biomarker responses in dual co-cultures grouped according to low biomarker levels in monocultures.

<p>Experimental Details are as per Figure 4. In this dataset, a common type of response was a synergistic increase based on a soluble factor(s) conferred by the presence of monocytes and uroepithelial cells, with low levels from monocultures absent in dual co-cultures. Statistical comparisons are: ⁺ control vs corresponding infected; ^# insert-containing infected co-culture vs corresponding infected monoculture; ^┴ insert-containing infected co-culture vs no insert infected co-culture, notations are p < 0.05; Mann–Whitney U-test.