<p><b>A</b>. .Bright field image of transgenic mouse liver section. <b>B</b>. DAPI staining of nuclei. <b>C</b>. Stained with anti-hAlb (green). <b>D</b>. Stained with anti-HCV (NS5) antibody (red). <b>E</b>. Merged sections that were stained with both anti-hAlb and anti-HCV (NS5) primary antibodies (yellow). <b>F</b>. Section from engrafted but not virus infected mouse liver stained with anti-hAlb and anti-HCV (NS5) primary antibodies.</p
Hepatitis C viruses (HCV) affect 170 million patients, but only a minority of patients develop sympt...
<p>(<b>A</b>) Structure of CN2-29<sup>(+/−)</sup>/MxCre<sup>(+/−)</sup> and the Cre-mediated activat...
<p>A–C: Detection of HCMV IE2 in red (A), DAPI to show total cells (B), and the two merged in C. D–F...
Hepatitis C virus (HCV) is the causative agent of most cases of chronic liver disease, cirrhosis, an...
In an attempt o establish a model for hepatitis C virus (HCV) infection, we produced mice transgenic...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis affecting over 170 million people worl...
<p>Liver sections from (A-B) mock infected or (C-F) HCV infected HIL mice 27 weeks post infection we...
<p>Mice transplanted with human hepatocytes for 8 weeks were inoculated with HBV (A) or HCV (B) huma...
<p>(A-H) Livers were harvested from mice in the mock and HCV infected groups, paraffin-embedded and ...
Hepatitis C virus (HCV) is a major cause of chronic liver disease including steatosis, cirrhosis and...
To assess the effects of constitutive hepatitis C virus (HCV) gene expression on liver, transgenic m...
<p><b>A</b>. Human hepatocytes are identified within the parenchyma of a chimeric mouse that had bee...
<div><p>(A) Immunohistochemical staining for FAS in liver tissue from an HCV-infected patient showin...
<p><b>A</b>: Co-localisation of NF-κB p65 immunoreactivity with B220 is indicated by arrows. (a–b) C...
COMMENTARY ON:A humanized mouse model to study hepatitis C virus infection, immune response and live...
Hepatitis C viruses (HCV) affect 170 million patients, but only a minority of patients develop sympt...
<p>(<b>A</b>) Structure of CN2-29<sup>(+/−)</sup>/MxCre<sup>(+/−)</sup> and the Cre-mediated activat...
<p>A–C: Detection of HCMV IE2 in red (A), DAPI to show total cells (B), and the two merged in C. D–F...
Hepatitis C virus (HCV) is the causative agent of most cases of chronic liver disease, cirrhosis, an...
In an attempt o establish a model for hepatitis C virus (HCV) infection, we produced mice transgenic...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis affecting over 170 million people worl...
<p>Liver sections from (A-B) mock infected or (C-F) HCV infected HIL mice 27 weeks post infection we...
<p>Mice transplanted with human hepatocytes for 8 weeks were inoculated with HBV (A) or HCV (B) huma...
<p>(A-H) Livers were harvested from mice in the mock and HCV infected groups, paraffin-embedded and ...
Hepatitis C virus (HCV) is a major cause of chronic liver disease including steatosis, cirrhosis and...
To assess the effects of constitutive hepatitis C virus (HCV) gene expression on liver, transgenic m...
<p><b>A</b>. Human hepatocytes are identified within the parenchyma of a chimeric mouse that had bee...
<div><p>(A) Immunohistochemical staining for FAS in liver tissue from an HCV-infected patient showin...
<p><b>A</b>: Co-localisation of NF-κB p65 immunoreactivity with B220 is indicated by arrows. (a–b) C...
COMMENTARY ON:A humanized mouse model to study hepatitis C virus infection, immune response and live...
Hepatitis C viruses (HCV) affect 170 million patients, but only a minority of patients develop sympt...
<p>(<b>A</b>) Structure of CN2-29<sup>(+/−)</sup>/MxCre<sup>(+/−)</sup> and the Cre-mediated activat...
<p>A–C: Detection of HCMV IE2 in red (A), DAPI to show total cells (B), and the two merged in C. D–F...