<i>Myd88</i>-dependency of enteropathy in <i>S</i>.Tm<sup>avir</sup> infected <i>Cybb</i><sup>−/−</sup> mice.
- Boas Felmy (470723)
- Pascal Songhet (149531)
- Emma Marie Caroline Slack (470724)
- Andreas J. Müller (211842)
- Marcus Kremer (78811)
- Laurye Van Maele (242338)
- Delphine Cayet (359668)
- Mathias Heikenwalder (79126)
- Jean-Claude Sirard (242339)
- Wolf-Dietrich Hardt (46235)
Publication date
October 2013
DOIAbstract
<p><i>Cybb</i><sup>−/−</sup><i>Myd88</i><sup>+/−</sup> mice or C<i>ybb</i><sup>−/−</sup><i>Myd88</i><sup>−/−</sup> littermates mice were pretreated with streptomycin and infected with <i>S</i>.Tm<sup>avir</sup> for 4 days. The bacterial loads in the gut lumen (A), the LP (red (B)) or the epithelial cells of the cecum (blue (B)), the degree of mucosal inflammation (C) and bacterial loads in the mLNs (D), livers (E) and spleens (F) were analyzed. *: p<0.05; **: p<0.01; ns: not significant; red line: median; dashed line: minimal detectable value.</p
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