Overexpression of ADAR1-p150 and IFN treatment-α.

<p>(A) Relative quantification of mRNA extracted from control cells (transfected with a control plasmid) and cells transfected with a plasmid overexpressing ADAR<i>-</i>p150. mRNA was quantified relatively to the control-transfected sample which was set as 1. Error bars indicate standard deviation (±SD,*p≤ 0.05). ADAR1-p150 levels were increased upon transfection however no increase in F11R expression was obtained upon p150 overexpression. (B) Relative quantification of mRNA extracted from control cells and cells treated with IFN-α. mRNA was quantified relatively to the control sample which was set as 1. ADAR1-p150 was increased upon treatment however no increase in F11R expression was obtained upon treatment. (C) Percentage of average RNA editing in F11R upon transfection with a p150-overexpressing plasmid. and upon IFN-α treatment. No significant changes were obtained in RNA editing in F11R.