Duration of each line of treatment.

<p>Figures in brackets represent lower and upper quartile limits.</p><p>Abbreviations: ADAP: Antidepressant and antipsychotic/antimanic drugs; p = p-value; H₀ = Null Hypothesis, H₁ = Alternative Hypothesis; M_T = the average duration of a LOT in TRD episodes, M_N = the average duration of a LOT in non-TRD episodes; LOT = Line of therapy.</p>a<p>An episode will have at least 3 lines of treatment to qualify as TRD, based on the definition stated in the Methods section.