<p>(A) Growth of <i>M.tuberculosis</i> and MtbΔ<i>mms</i> in broth culture. <i>M.tuberculosis</i> and MtbΔ<i>mms</i> strains were cultured separately in MB7H9 medium at 37°C/200 rpm for 13 days. <i>M.tuberculosis</i> and MtbΔ<i>mms</i> exhibited similar growth pattern in MB7H9 broth culture. (B) Growth of <i>M.tuberculosis</i> and MtbΔ<i>mms</i> in human THP-1 macrophages. THP-1 cells were infected with <i>M.tuberculosis</i> or Mtb∆<i>mms</i> mutant separately at an MOI of 1:1. The number of intracellular viable bacteria was determined for 6 days. The figure represents the CFU data of <i>M.tuberculosis</i> and MtbΔ<i>mms</i> obtained on MB7H11 plates. Mtb∆<i>mms</i> mutant exhibited a significant attenuation in its growth when compared with...
International audienceIsolates of the human pathogen Mycobacterium tuberculosis recovered from clini...
<p>(<b>A</b>) Effects of MtTAG on the ATPase activity of MsParA. (<b>B</b>) Effects of MtTAG and its...
Using phosphorimager technology to quantitate differences in protein expression, we have investigate...
<p>(A) Confirmation of <i>sapM</i> gene deletion in <i>M.tuberculosis</i> by PCR. PCR was carried ou...
<p><b>A. </b><i>M. tuberculosis</i> H37Rv wild-type (WT) and the PMM168 mutant strain were grown in ...
The in vivo rate of proliferation of Mycobacterium tuberculosis, the causative agent of tuberculosis...
<p>(A) Influence of <i>sapM</i> deletion on the growth of <i>M.tuberculosis</i> in THP-1 cells. THP-...
<p>THP-1 cells were infected with wild-type <i>M.tuberculosis</i>, MtbΔ<i>end</i>, MtbΔ<i>xthA</i> o...
Tuberculosis (TB) is responsible for nearly 1.4 million deaths globally every year and continues to ...
<p>(<b>A</b>) <i>M</i>. <i>tuberculosis</i> WT, Δ<i>pstS1</i>, and Δ<i>pstS1</i> pMV<i>pstS1</i> wer...
Protein tyrosine kinases and tyrosine phosphatases from several bacterial pathogens have been shown...
<p>(<b>A</b>) Intracellular survival of <i>Mtb</i> strains. Macrophages were infected with <i>Mtb</i...
Very little is known about the culturability and viability of mycobacteria following their phagocyto...
Isolates of the human pathogen Mycobacterium tuberculosis recovered from clinical samples exhibit ge...
<div><p>Background</p><p>The failure of <i>Mycobacterium bovis</i> Bacille Calmette-Guérin to impart...
International audienceIsolates of the human pathogen Mycobacterium tuberculosis recovered from clini...
<p>(<b>A</b>) Effects of MtTAG on the ATPase activity of MsParA. (<b>B</b>) Effects of MtTAG and its...
Using phosphorimager technology to quantitate differences in protein expression, we have investigate...
<p>(A) Confirmation of <i>sapM</i> gene deletion in <i>M.tuberculosis</i> by PCR. PCR was carried ou...
<p><b>A. </b><i>M. tuberculosis</i> H37Rv wild-type (WT) and the PMM168 mutant strain were grown in ...
The in vivo rate of proliferation of Mycobacterium tuberculosis, the causative agent of tuberculosis...
<p>(A) Influence of <i>sapM</i> deletion on the growth of <i>M.tuberculosis</i> in THP-1 cells. THP-...
<p>THP-1 cells were infected with wild-type <i>M.tuberculosis</i>, MtbΔ<i>end</i>, MtbΔ<i>xthA</i> o...
Tuberculosis (TB) is responsible for nearly 1.4 million deaths globally every year and continues to ...
<p>(<b>A</b>) <i>M</i>. <i>tuberculosis</i> WT, Δ<i>pstS1</i>, and Δ<i>pstS1</i> pMV<i>pstS1</i> wer...
Protein tyrosine kinases and tyrosine phosphatases from several bacterial pathogens have been shown...
<p>(<b>A</b>) Intracellular survival of <i>Mtb</i> strains. Macrophages were infected with <i>Mtb</i...
Very little is known about the culturability and viability of mycobacteria following their phagocyto...
Isolates of the human pathogen Mycobacterium tuberculosis recovered from clinical samples exhibit ge...
<div><p>Background</p><p>The failure of <i>Mycobacterium bovis</i> Bacille Calmette-Guérin to impart...
International audienceIsolates of the human pathogen Mycobacterium tuberculosis recovered from clini...
<p>(<b>A</b>) Effects of MtTAG on the ATPase activity of MsParA. (<b>B</b>) Effects of MtTAG and its...
Using phosphorimager technology to quantitate differences in protein expression, we have investigate...