<p>Sequence analysis of the LibA and LibB mutants and evolution of the mutation frequency at each step of the screening protocol. The numbers N and n correspond to the number of isolated clones and sequenced mutants at each step, respectively.</p
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
<p>(A) Sequence strength influenced by mutation of each single site. Red indicates positive mutation...
Number of LCYE-A and LCYE-B mutants identified (specific primers in Table 2), with their correspondi...
<p>Primer sequences of the 6 primers used and the mutation frequency detected.</p
<p>(A) Approximately 90 clones were sequenced per library of promoters. (Top) Sequenced clones from ...
Number of transitions and transversion of nucleotide in genotyping by sequencing analysis.</p
<p>Note:</p><p>1. Sequences of No. 198-456 amino acids of LBP: CEMIQKSVSSDLQPYLQTLPVTTEIDSFADIDYSLVE...
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
(A) FACS plots illustrating the process of library screening. In the first sorting, ACE-2-positive m...
<p>(A) Frequencies of particular nucleotide substitutions within light-chain gene. (B) A graphical v...
<p>The fraction of mutations is plotted as a function of selection stringency (where a high tetracyc...
<p>List of mutants in histone deacetylases, the mutagenesis strategies, and corresponding TIGR CAG c...
Each row lists the corresponding primer sequences and annealing temperature used in the mutagenesis ...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
<p>(A) Sequence strength influenced by mutation of each single site. Red indicates positive mutation...
Number of LCYE-A and LCYE-B mutants identified (specific primers in Table 2), with their correspondi...
<p>Primer sequences of the 6 primers used and the mutation frequency detected.</p
<p>(A) Approximately 90 clones were sequenced per library of promoters. (Top) Sequenced clones from ...
Number of transitions and transversion of nucleotide in genotyping by sequencing analysis.</p
<p>Note:</p><p>1. Sequences of No. 198-456 amino acids of LBP: CEMIQKSVSSDLQPYLQTLPVTTEIDSFADIDYSLVE...
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
(A) FACS plots illustrating the process of library screening. In the first sorting, ACE-2-positive m...
<p>(A) Frequencies of particular nucleotide substitutions within light-chain gene. (B) A graphical v...
<p>The fraction of mutations is plotted as a function of selection stringency (where a high tetracyc...
<p>List of mutants in histone deacetylases, the mutagenesis strategies, and corresponding TIGR CAG c...
Each row lists the corresponding primer sequences and annealing temperature used in the mutagenesis ...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
<p>(A) Sequence strength influenced by mutation of each single site. Red indicates positive mutation...