Constrained principal component analysis loadings for the 7 neonatal clinical factors to explain variance in cortical thickness.

<p>Predictor loadings were computed as correlations between component scores and the set of neonatal clinical variables.</p><p>C.I. = 95% confidence interval; Pain = number of skin-breaking procedures exposure; Morphine = cumulative daily dose in milligrams adjusted for daily body weight; Ventilation = number of days on mechanical ventilation; Surgery = number of surgeries; Infection = number of culture proven infection; SNAP-II = score for neonatal acute physiology; GA = gestational age.</p>†<p><i>p</i>-value threshold for significance adjusted for multiple comparisons with a false discovery rate (FDR) correction set at 5%; <i>p</i>-values and confidence intervals were computed by bootstrapping 1000 times.