Influence of TFF3 on forelimb wire-hanging duration in cerebral ischemia/reperfusion injury.

<p>(<b>A</b>) Graphic representation of the left forelimb wire-hanging duration. Blue and red: Wild-type mice with sham operation or cerebral injury, respectively. Purple and green: Cerebrum-injured TFF3^-/- mice with administration of PBS or recombinant TFF3, respectively. P<0.001 between wild-type mice with sham operation (blue) and cerebral injury (red), P<0.001 between wild-type (red) and TFF3^-/- (purple) mice with cerebral injury, and P<0.001 between cerebrum-injured TFF3^-/- mice with administration of PBS (purple) and recombinant TFF3 (green) at day 5, 10, and 30 days by ANOVA (n = 8). (<b>B</b>) Graphic representation of the right forelimb wire-hanging duration. The bar-color representations are the same as those for panel A. P>0.05 between wild-type mice with sham operation (blue) and cerebral injury (red), P>0.05 between wild-type (red) and TFF3^-/- (purple) mice with cerebral injury, and P<0.05 between cerebrum-injured TFF3^-/- mice with administration of PBS (purple) and recombinant TFF3 (green) at day 5, 10, and 30 days by ANOVA (n = 8).