Influence of TFF3 on the forelimb gripping strength in cerebral ischemia/reperfusion injury.

<p>(<b>A</b>) Experimental records of the left and right forelimb gripping strengths from sham-operated and cerebrum-injured (CI) wild-type mice and cerebrum-injured TFF3^-/- mice with administration of PBS or recombinant TFF3. (<b>B</b>) Graphic representation of the gripping strengths of the left and right forelimbs. Blue and red: Wild-type mice with sham operation or cerebral injury, respectively. Purple and green: TFF3^-/- mice with cerebral injury with administration of PBS or recombinant TFF3, respectively. For the left forelimb, P<0.005 between wild-type mice with sham operation (blue) and cerebral injury (red), P<0.01 between wild-type (red) and TFF3^-/- (purple) mice with cerebral injury, and P<0.001 between cerebrum-injured TFF3^-/- mice with administration of PBS (purple) and recombinant TFF3 (green) at day 5, 10, and 30 days by ANOVA (n = 8). For the right forelimb, P>0.05 between wild-type mice with sham operation (blue) and cerebral injury (red), P>0.05 between wild-type (red) and TFF3^-/- (purple) mice with cerebral injury, and P<0.05 between cerebrum-injured TFF3^-/- mice with administration of PBS (purple) and recombinant TFF3 (green) at day 5, 10, and 30 days by ANOVA (n = 8).