M2 macrophages increase in the mucosa of chronic UC patients.

<p>A) Representative photographs showing CD68, CD86 and CD206 immunostaining in paraffin-embedded sections of damaged and non-damaged mucosa of patients with UC, magnification 60X. B) Graphs show quantitative analysis of CD68, CD86 and CD206 positive cells performed in a total area of 0.3 mm² of consecutive slides. Bars represent mean±SEM. *<i>P</i><0.05 and ***<i>P</i><0.001 vs the respective non-damaged mucosa and ^##<i>P</i><0.01 and ^###<i>P</i><0.001 vs the respective mucosa in newly diagnosed patients. C) Graphs show percentage of CD86+/CD68+ cells and CD206+/CD68+ cells in newly diagnosed (n=8) and chronic patients with UC (n=12). Bars represent mean±SEM. *<i>P</i><0.05 <i>vs</i> the respective non-damaged mucosa and ^&&<i>P</i><0.01 and ^&&&<i>P</i><0.001 <i>vs</i> the CD86/CD68 in the respective mucosa in the same graph.