Relative rate of evolution of the UL32 gene based on amino acid-sequence.

<p>The mean evolutionary rate per amino acid site within the UL32 gene was calculated to identify genomic regions with a more than average genomic variation. Relative evolutionary rates are shown for each site next to the site number. These rates are scaled such that the average evolutionary rate across all sites is 1 (dotted line). This means that sites showing a rate < 1 are evolving slower than average and those with a rate > 1 are evolving faster than average. These relative rates were estimated with the use of MEGA under the Jones-Taylor-Thornton model (+G) (21). Known immunogenic epitopes are indicated by horizontal bars above the graph [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078925#B28" target="_blank">28</a>-<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078925#B30" target="_blank">30</a>].