The composition of bacteria and bacteria-derived EV in small intestinal fluids following 3% DSS administration.

<p>For all figures, bacteria and EV were isolated from small intestinal fluids of mice before (D0) and 5 days (D5) after 3% DSS oral administration (each group = 5). (A) EV TEM images (×100 k, left panel) and protein profiles through SDS-PAGE by using coomassie brilliant blue G250 dye (right panel). (B) Operational taxonomic units (OTUs) of bacteria and bacterial EV using Roche 454 GS FLX Titanium. For figures (C)–(E), the proportion of bacteria and bacterial EV in small intestinal fluids is displayed at the phylum (C), genus (D), and species (E) levels. As for genus and species, the proportion less than 1% occupancy is noted as others.