Methylation change relative to nearest Transcriptional Start Site (TSS).

<p>Each point represents a methylation site as measured by MSCC analysis and that passed the filters described in the methods section. Vertical axis represents change of methylation in hypoxic treated sample relative to control sample. Horizontal axis is distance from nearest TSS, where negative is upstream and positive is downstream. Green sites fall within a CpG island, in addition to being in the promoter region of a gene.