Genome wide methylation assay of the <i>Mus Musculus</i> genome.

<p>DNA extracted from post-hypoxic and control cell cultures underwent a Methyl Sensitive Cut Counting assay as described in the methods. Vertical axis signifies average methylation of hypoxic sample while the horizontal axis signifies average methylation of control sample in all sub-figures. (a) Each point represents a measured site (CCGG) that conforms to the following conditions: greater than 30 reads in red, greater than 60 reads in green and greater than 100 reads in blue. (b) All measured methylation sites with greater than 30 reads in addition to falling within the promoter region of a gene (Defined as 1500bp upstream of Transcriptional Start Site (TSS) to 500bp downstream of the TSS.) (c) All measured sites that fall within a CpG island in addition to having more than 30 reads at the given locus. (d) Observed sites with various levels of methylation change in Promoter regions and CpG islands.