Microarray analysis of miRNAs in control and ACTH, 17α-E2 and DEX treated rat adrenals.

<p>[A]. Frequency of expressed values. These data show the reproducibility and consistancy among all the samples. [B]. 3-D View of Principal Component Analysis (PCA) showing distinguished clusters between control and ACTH, 17α-E2 and DEX treated adrenals. The PCA was performed on differentially expressed genes between control and ACTH, 17α-E2 and DEX treated adrenals. Adrenals without or with ACTH, 17α-E2 or DEX are represented by different colors i.e., green for control, blue for ACTH, red for 17α-E2 and purple for DEX. The control, ACTH, 17α-E2 and DEX treated adrenals clustered into different and distinct groups. [C]. Venn diagram representing differentially expressed miRNAs observed in the comparisons among the adrenals treated with ACTH, 17α-E2 or DEX.