BBR mass spectrographic behavior and its metabolism in tissues.

Relative percent of 4R metabolites in human (A) and rat (B) microsomal samples.

Wanda Vélez-Carrasco (712726)
Carol E. Green (399919)
Paul Catz (712727)
Anna Furimsky (712728)
Kathleen O’Loughlin (712729)
Vesna A. Eterović (184266)
P. A. Ferchmin (712730)

March 2015

50 μM 4R microsomal human and rat samples were incubated for 5, 15, and 30 min. 4R metabolites le...

Typical 600 MHz 1H-NMR spectra from a control rat.

Marie Tremblay-Franco (414181)
Nicolas J. Cabaton (413918)
Cécile Canlet (185237)
Roselyne Gautier (820337)
Cheryl M. Schaeberle (820338)
Fabien Jourdan (216798)
Carlos Sonnenschein (48060)
Florence Vinson (820339)
Ana M. Soto (68738)
Daniel Zalko (386064)

October 2015

A) Serum sample. B) Aqueous liver extract sample. Peak 1, low-density-lipoproteins/very-lo...

PR analysis of 1H-NMR spectra of rat liver tissues.

Miao Wang (248377)
Fei Wang (19534)
Yinan Wang (478812)
Xiaonan Ma (478813)
Min Zhao (66793)
Chunjie Zhao (337669)

November 2013

(A): PCA analysis of the spectra of liver tissues from normal and hyperlipidemia rats (R2</s...

Concentration of BBR and its metabolites (M1, M2, M3, M4) in HFD rat liver and plasma (Mean ± SEM, n = 6).

Hong-Mei Yan (305065)
Ming-Feng Xia (781250)
Yan Wang (15435)
Xin-Xia Chang (781251)
Xiu-Zhong Yao (781252)
Sheng-Xiang Rao (781253)
Meng-Su Zeng (781254)
Yin-Fang Tu (781255)
Ru Feng (422848)
Wei-Ping Jia (54227)
Jun Liu (42548)
Wei Deng (17330)
Jian-Dong Jiang (346645)
Xin Gao (14001)

August 2015

Concentration of BBR and its metabolites (M1, M2, M3, M4) in HFD rat liver and plasma (Mean ± SEM...

Tissue distribution of metabolites of BBR.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

3A Profiles of BBR and its metabolites in liver distribution in SD rats after oral administration...

Tissue distribution of BBR.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

2A Plasma concentration-time profile of BBR after oral administration of 200 mg/kg in 48 h (n = 6...

Chromatograms and kinetic behavior of BBR in the three cell lines.

Yu-Nong Pang (662160)
Yin-Wen Liang (662161)
Tian-Shi Feng (638258)
Shuang Zhao (484057)
Hao Wu (65943)
Yu-Shuang Chai (288661)
Fan Lei (288658)
Yi Ding (172783)
Dong-Ming Xing (288664)
Li-Jun Du (288666)

November 2014

(A–C) HPLC chromatograms. (A) Standard BBR; (B) Blank sample from BBR treated cells; (C) Samples ...

Base peak intensity (BPI) chromatograms of plasma metabolite profiles from (A) a control rat and (B) a model rat measured by HILIC-UHPLC/MS.

Longshan Zhao (544964)
Zhili Xiong (5663854)
Xiumei Lu (755545)
Shuning Zheng (755546)
Fang Wang (105926)
Lin Ge (339910)
Guangyue Su (755547)
Jingyu Yang (666642)
Chunfu Wu (755548)

June 2015

Base peak intensity (BPI) chromatograms of plasma metabolite profiles from (A) a control rat and ...

AUC (0-t) values of tissues and tissue/plasma ratios of BBR and its metabolites.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

AUC (0-t) values of tissues and tissue/plasma ratios of BBR and its metabolites.</p

LC-MS/MS profiles of serum samples with BBR introduced in silico and in vivo.

Beth Buchanan (5007821)
Qingfang Meng (5007824)
Mathieu-Marc Poulin (5007830)
Jonathan Zuccolo (252930)
Chike Godwin Azike (5007818)
Joseph Gabriele (5007827)
David Charles Baranowski (5007815)

March 2018

Chromatograms of (A) blank serum (B) blank serum spiked with (1) d6-BBR (31.25 ng/mL) and (2) BBR...

Liver biochemistry in sham or CBDL rats treated with vehicle or BBG.

Hung-Chun Tung (733431)
Fa-Yauh Lee (115194)
Sun-Sang Wang (431898)
Ming-Hung Tsai (220365)
Jing-Yi Lee (431897)
Teh-Ia Huo (115192)
Hui-Chun Huang (383485)
Chiao-Lin Chuang (431899)
Han-Chieh Lin (115193)
Shou-Dong Lee (383488)

May 2015

AST: aspartate transaminase; ALT: aspartate transaminaseaP<0.01 v...

Clinical chemistry of liver and kidney function in chronically administered animals.

Beth Buchanan (5007821)
Qingfang Meng (5007824)
Mathieu-Marc Poulin (5007830)
Jonathan Zuccolo (252930)
Chike Godwin Azike (5007818)
Joseph Gabriele (5007827)
David Charles Baranowski (5007815)

March 2018

Male Sprague-Dawley rats (N = 4/group) received once daily for 14 days administration of 90 mg/kg...

Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

<div>Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholest...

Tissue distribution of berberine and its metabolites after oral administration in rats.

Xiang-Shan Tan
Jing-Yi Ma
Ru Feng
Chao Ma
Wen-Jing Chen
Yu-Peng Sun
Jie Fu
Min Huang
Chi-Yu He
Jia-Wen Shou
Wen-Yi He
Yan Wang
Jian-Dong Jiang

Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-low...

The relative concentrations of marker metabolites acquired by HR-MAS 1H NMR spectroscopy from basal cell carcinoma (BCC) and normal skin tissue (NST).

Je-Ho Mun (2549863)
Heonho Lee (2549875)
Dahye Yoon (2549869)
Byung-Soo Kim (1501063)
Moon-Bum Kim (2549866)
Shukmann Kim (2549872)

March 2016

Metabolites that were significantly different between tissues are shown in bold.</p

Relative percent of 4R metabolites in human (A) and rat (B) microsomal samples.

Wanda Vélez-Carrasco (712726)
Carol E. Green (399919)
Paul Catz (712727)
Anna Furimsky (712728)
Kathleen O’Loughlin (712729)
Vesna A. Eterović (184266)
P. A. Ferchmin (712730)

March 2015

50 μM 4R microsomal human and rat samples were incubated for 5, 15, and 30 min. 4R metabolites le...

Typical 600 MHz 1H-NMR spectra from a control rat.

Marie Tremblay-Franco (414181)
Nicolas J. Cabaton (413918)
Cécile Canlet (185237)
Roselyne Gautier (820337)
Cheryl M. Schaeberle (820338)
Fabien Jourdan (216798)
Carlos Sonnenschein (48060)
Florence Vinson (820339)
Ana M. Soto (68738)
Daniel Zalko (386064)

October 2015

A) Serum sample. B) Aqueous liver extract sample. Peak 1, low-density-lipoproteins/very-lo...

PR analysis of 1H-NMR spectra of rat liver tissues.

Miao Wang (248377)
Fei Wang (19534)
Yinan Wang (478812)
Xiaonan Ma (478813)
Min Zhao (66793)
Chunjie Zhao (337669)

November 2013

(A): PCA analysis of the spectra of liver tissues from normal and hyperlipidemia rats (R2</s...

Concentration of BBR and its metabolites (M1, M2, M3, M4) in HFD rat liver and plasma (Mean ± SEM, n = 6).

Hong-Mei Yan (305065)
Ming-Feng Xia (781250)
Yan Wang (15435)
Xin-Xia Chang (781251)
Xiu-Zhong Yao (781252)
Sheng-Xiang Rao (781253)
Meng-Su Zeng (781254)
Yin-Fang Tu (781255)
Ru Feng (422848)
Wei-Ping Jia (54227)
Jun Liu (42548)
Wei Deng (17330)
Jian-Dong Jiang (346645)
Xin Gao (14001)

August 2015

Concentration of BBR and its metabolites (M1, M2, M3, M4) in HFD rat liver and plasma (Mean ± SEM...

Tissue distribution of metabolites of BBR.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

3A Profiles of BBR and its metabolites in liver distribution in SD rats after oral administration...

Tissue distribution of BBR.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

2A Plasma concentration-time profile of BBR after oral administration of 200 mg/kg in 48 h (n = 6...

Chromatograms and kinetic behavior of BBR in the three cell lines.

Yu-Nong Pang (662160)
Yin-Wen Liang (662161)
Tian-Shi Feng (638258)
Shuang Zhao (484057)
Hao Wu (65943)
Yu-Shuang Chai (288661)
Fan Lei (288658)
Yi Ding (172783)
Dong-Ming Xing (288664)
Li-Jun Du (288666)

November 2014

(A–C) HPLC chromatograms. (A) Standard BBR; (B) Blank sample from BBR treated cells; (C) Samples ...

Base peak intensity (BPI) chromatograms of plasma metabolite profiles from (A) a control rat and (B) a model rat measured by HILIC-UHPLC/MS.

Longshan Zhao (544964)
Zhili Xiong (5663854)
Xiumei Lu (755545)
Shuning Zheng (755546)
Fang Wang (105926)
Lin Ge (339910)
Guangyue Su (755547)
Jingyu Yang (666642)
Chunfu Wu (755548)

June 2015

Base peak intensity (BPI) chromatograms of plasma metabolite profiles from (A) a control rat and ...

AUC (0-t) values of tissues and tissue/plasma ratios of BBR and its metabolites.

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

AUC (0-t) values of tissues and tissue/plasma ratios of BBR and its metabolites.</p

LC-MS/MS profiles of serum samples with BBR introduced in silico and in vivo.

Beth Buchanan (5007821)
Qingfang Meng (5007824)
Mathieu-Marc Poulin (5007830)
Jonathan Zuccolo (252930)
Chike Godwin Azike (5007818)
Joseph Gabriele (5007827)
David Charles Baranowski (5007815)

March 2018

Chromatograms of (A) blank serum (B) blank serum spiked with (1) d6-BBR (31.25 ng/mL) and (2) BBR...

Liver biochemistry in sham or CBDL rats treated with vehicle or BBG.

Hung-Chun Tung (733431)
Fa-Yauh Lee (115194)
Sun-Sang Wang (431898)
Ming-Hung Tsai (220365)
Jing-Yi Lee (431897)
Teh-Ia Huo (115192)
Hui-Chun Huang (383485)
Chiao-Lin Chuang (431899)
Han-Chieh Lin (115193)
Shou-Dong Lee (383488)

May 2015

AST: aspartate transaminase; ALT: aspartate transaminaseaP<0.01 v...

Clinical chemistry of liver and kidney function in chronically administered animals.

Beth Buchanan (5007821)
Qingfang Meng (5007824)
Mathieu-Marc Poulin (5007830)
Jonathan Zuccolo (252930)
Chike Godwin Azike (5007818)
Joseph Gabriele (5007827)
David Charles Baranowski (5007815)

March 2018

Male Sprague-Dawley rats (N = 4/group) received once daily for 14 days administration of 90 mg/kg...

Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats

Xiang-Shan Tan (478669)
Jing-Yi Ma (478670)
Ru Feng (422848)
Chao Ma (207385)
Wen-Jing Chen (321277)
Yu-Peng Sun (478671)
Jie Fu (478672)
Min Huang (161268)
Chi-Yu He (478673)
Jia-Wen Shou (478674)
Wen-Yi He (478675)
Yan Wang (15435)
Jian-Dong Jiang (346645)

October 2013

<div>Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholest...

Tissue distribution of berberine and its metabolites after oral administration in rats.

Xiang-Shan Tan
Jing-Yi Ma
Ru Feng
Chao Ma
Wen-Jing Chen
Yu-Peng Sun
Jie Fu
Min Huang
Chi-Yu He
Jia-Wen Shou
Wen-Yi He
Yan Wang
Jian-Dong Jiang

Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-low...

The relative concentrations of marker metabolites acquired by HR-MAS 1H NMR spectroscopy from basal cell carcinoma (BCC) and normal skin tissue (NST).

Je-Ho Mun (2549863)
Heonho Lee (2549875)
Dahye Yoon (2549869)
Byung-Soo Kim (1501063)
Moon-Bum Kim (2549866)
Shukmann Kim (2549872)

March 2016

Metabolites that were significantly different between tissues are shown in bold.</p

Relative percent of 4R metabolites in human (A) and rat (B) microsomal samples.

Wanda Vélez-Carrasco (712726)
Carol E. Green (399919)
Paul Catz (712727)
Anna Furimsky (712728)
Kathleen O’Loughlin (712729)
Vesna A. Eterović (184266)
P. A. Ferchmin (712730)

March 2015

50 μM 4R microsomal human and rat samples were incubated for 5, 15, and 30 min. 4R metabolites le...

Typical 600 MHz 1H-NMR spectra from a control rat.

Marie Tremblay-Franco (414181)
Nicolas J. Cabaton (413918)
Cécile Canlet (185237)
Roselyne Gautier (820337)
Cheryl M. Schaeberle (820338)
Fabien Jourdan (216798)
Carlos Sonnenschein (48060)
Florence Vinson (820339)
Ana M. Soto (68738)
Daniel Zalko (386064)

October 2015

A) Serum sample. B) Aqueous liver extract sample. Peak 1, low-density-lipoproteins/very-lo...

PR analysis of 1H-NMR spectra of rat liver tissues.

Miao Wang (248377)
Fei Wang (19534)
Yinan Wang (478812)
Xiaonan Ma (478813)
Min Zhao (66793)
Chunjie Zhao (337669)

November 2013

(A): PCA analysis of the spectra of liver tissues from normal and hyperlipidemia rats (R2</s...

BBR mass spectrographic behavior and its metabolism in tissues.

Abstract

Extracted data

BBR mass spectrographic behavior and its metabolism in tissues.

Abstract

Extracted data

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