Thermotaxis memory behavior of mutants for genes required for serotonin synthesis.

<p>(A) Thermotaxis memory assay model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077779#pone.0077779-Ye2" target="_blank">[7]</a>. (B) Extinction of the association (food at 20°C) of mutant animals. The normalized isothermal tracking behavior (IT) values were used. (C) Comparison of the extinctions of wild-type and mutant animals at the time interval of 18-hr. (D) Thermotaxis behavior of wild-type and mutant animals. In the thermotaxis assay system, movement to 25°C was scored as thermophilic (T); movement to 17°C was scored as cryophilic (C); movement across the thermal gradient (17°C/25°C) was scored as athermotactic (A); and movement at 20°C was scored as IT. (E–F) Genetic interaction of <i>tph-1</i> with <i>bas-1</i> in regulating thermotaxis memory. Bars represent means ± S.E.M. **<i>p</i><0.01.